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Search Results for " related tyrosine kinase "

Targets

36

Compounds

43

Recombinant Proteins

2

Libraries

Cat No. Product Name Synonyms Targets
T4209 TAK-659 hydrochloride TAK-659 VEGFR , FLT , Tyrosine Kinases , JAK , Syk
TAK-659 hydrochloride (TAK-659) is a potent and selective inhibitor of spleen tyrosine kinase (SYK) with an IC50 value of 3.2 nM. It is selective against most other kinases, but potent toward both SYK and FLT3.
T14364 AZ-Dyrk1B-33 3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine DYRK
AZ-Dyrk1B-33 (3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine) is a potent and selective Dyrk1B kinase inhibitor with an IC50 of 7 nM.
T4257 Belizatinib TSR-011 Trk receptor , ALK
Belizatinib (TSR-011) is an effective, oral and dual inhibitor of ALK (IC50: 0.7 nM, wild-type recombinant ALK) and TRKA, TRKB, and TRKC.
T4071 Repotrectinib TPX-0005,TPX 0005,TPX0005 Trk receptor , ROS , Src , ALK , ROS Kinase
Repotrectinib (TPX-0005) is a potent ALK/ROS1/TRK inhibitor, with IC50 of 1.01 nM, 5.3 nM, 1.08 nM and 1.26 nM for WT ALK, SRC, ALK L1196M and ALK G1202R, respectively.
T6052 GW 441756 Apoptosis , Raf , Trk receptor , CDK
GW 441756 is a specific Tropomyosin-related kinase A (TrkA) inhibitor with an IC50 value of 2 nM.
T3678 Entrectinib RXDX-101,NMS-E628 Trk receptor , ROS , ALK , Autophagy , ROS Kinase
Entrectinib (RXDX-101) is an inhibitor of TrkA (IC50: 1.7 nM), TrkB (IC50: 0.1 nM), and TrkC (IC50: 0.1 nM), as well as anaplastic lymphoma kinase (ALK; IC50: 1.6 nM) and C-ros oncogene 1 (ROS1; IC50: 0.2 nM). Entrectini...
T2054 Altiratinib DCC-2701 VEGFR , Tie-2 , FLT , Trk receptor , c-Met/HGFR
Altiratinib (DCC-2701)(DCC-2701) is a novel c-MET/TIE-2/VEGFR inhibitor; effectively reduce tumor burden in vivo and block c-MET pTyr(1349)-mediated signaling, cell growth and migration as compared with an HGF antagonist...
T4349 Sitravatinib MG516,MGCD516 Discoidin Domain Receptor (DDR) , VEGFR , FLT , Trk receptor , TAM Receptor , c-Kit , Ephrin Receptor
Sitravatinib (MGCD516) (MGCD516) is an inhibitor targeting multiple RTKs involved in driving sarcoma cell growth, including c-Met, c-Kit, PDGFRα/β, PDGFR, and Axl.
T6712 Tyrphostin AG 879 AG 879 Apoptosis , EGFR , Trk receptor , HER , PDGFR
Tyrphostin AG 879 (AG 879) effectively inhibits HER2/ErbB2 (IC50: 1 μM), 100- and 500-fold higher selective to ErbB2 than EGFR and PDGFR.
T14692 BMX-IN-1 BMX kinase inhibitor BTK
BMX-IN-1 (BMX kinase inhibitor) is a selective inhibitor of bone marrow tyrosine kinase on chromosome X (BMX, IC50 = 8 nM) and the related Bruton’s tyrosine kinase (BTK, IC50 = 10.4 nM), but BMX-IN-1 is more than 47-656 ...
T4409 Gilteritinib ASP2215 FLT , TAM Receptor , c-Kit
Gilteritinib (ASP2215) is a potent inhibitor at the FMS-related tyrosine kinase 3 (FLT3) and AXL tyrosine kinase receptors (IC50 = 0.29 nM and <1 nM, respectively). In preClinicalal studies, gilteritinib showed strong an...
T7493 AG-13958 AG-013958 VEGFR
AG-13958 (AG-013958) (AG-013958), a potent VEGFR tyrosine kinase inhibitor, for the treatment of age-related macular degeneration.
T1895 SKLB 610 VEGFR , FGFR , PDGFR
SKLB610, a novel multi-targeted inhibitor, inhibits angiogenesis-related tyrosine kinase VEGFR2, FGFR2, and PDGFR at a rate of 97%, 65%, and 55%, respectively, at the concentration of 10 μM in biochemical kinase assays.
T79860 TIE-2/VEGFR-2 kinase-IN-5 VEGFR , Tie-2
TIE-2/VEGFR-2 kinase-IN-5 is a potent TIE-2 and VEGFR-2 tyrosine kinase receptor inhibitor with anti-angiogenic activity and is commonly used in biomedical research related to angiogenesis.
T9473 4SC-203 FLT
4SC-203 is a multikinase inhibitor with potential antineoplastic activity. 4SC-203 selectively inhibits FMS-related tyrosine kinase 3 (FLT3/STK1), FLT3 mutated forms, and vascular endothelial growth factor receptors (VEG...
T7568 LM22A-4 Trk receptor
LM22A-4 is a brain-derived neurotrophic factor (BDNF) mimetic and agonist of the receptor tropomyosin-related kinase B (TrkB; IC50 : 47 nM in a fluorescence anisotropy assay)
TQ0271 Falnidamol BIBX 1382 EGFR
Falnidamol (BIBX 1382) is an orally active, selective EGFR tyrosine kinase inhibitor with an IC50 of 3 nM. Falnidamol displays > 1000-fold lower potency against ErbB2 (IC50=3.4 μM) and a range of other related tyrosine k...
T4391 Syk Inhibitor II dihydrochloride Syk Inhibitor II (hydrochloride) Others , Tyrosine Kinases , Syk , PKC , BTK
Spleen tyrosine kinase (Syk) is a non-receptor tyrosine kinase that, upon phosphorylation, binds to immunoreceptor tyrosine-based activation motifs of FcRγ chains and mediates downstream signaling related to platelet fun...
T10870L CP-547632 VEGFR , FGFR , PDGFR , BTK
CP-547632 is an orally available and potent, ATP-competitive dual inhibitor of VEGFR-2 and FGF kinase F with IC50s of 11 nM and 9 nM, respectively. CP-547632 is selective, with higher selectivity for VEGFR2 and bFGF than...
T3626 Acalabrutinib ACP-196 BTK
Acalabrutinib (ACP-196), also known as ACP-196, is an orally available inhibitor of Bruton's tyrosine kinase (BTK) with potential antineoplastic activity. Upon administration, ACP-196 inhibits the activity of BTK and pre...
T2514 Linifanib ABT-869,RG3635,AL-39324 Apoptosis , c-Fms , VEGFR , FLT , CSF-1R , PDGFR , c-Kit , Autophagy
Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) and PDGFRβ (IC50: 66 nM). Linifanib may exhibit potent antiprolife...
T22552 AD57 (hydrochloride) Others
AD57, as polypharmacological cancer therapeutic, is designed to regulate multiple targets related to cancer blocks the receptor tyrosine kinase RET in Drosophila (IC50: 2 nM). AD57 effectively suppresses tyrosine kinase ...
T62447 Paltimatrectinib PBI-200,PPI-5278 Trk receptor , Tyrosine Kinases
Paltimatrectinib (PBI-200) is a potent tyrosine kinase inhibitor with anticancer activity that inhibits myosin-related kinase A (TrkA).Paltimatrectinib is used in the study of bladder, breast and colorectal cancers.
T71400 Quizartinib HCl
Quizartinib, also know as AC220 and AC010220, is an orally available FLT3 / STK1 inhibitor with potential antineoplastic activity. Class III receptor tyrosine kinase inhibitor AC220 selectively inhibits class III recept...
T37079 VEGFR2 Kinase Inhibitor II
Vascular endothelial growth factor receptor 2 (VEGFR2, also known as KDR and FLK1) is a receptor tyrosine kinase that regulates angiogenesis, vascular development, and embryonic hematopoiesis in response to VEGF isoforms...
T78209 Nedometinib MEK
Nedometinib, a tyrosine kinase inhibitor, specifically targets MEK1 and exhibits antineoplastic effects. It is utilized in research related to dermatosis, cutaneous fibroneruroma, and neurofibromatosis [1].
T35334 CH7233163 EGFR
CH7233163 is a useful organic compound for research related to life sciences and the catalog number is T35334.
T73942 (Rac)-IBT6A hydrochloride
(Rac)-IBT6A hydrochloride is a racemic mixture comprising IBT6A hydrochloride, which itself is an impurity of Ibrutinib. This compound plays a role in the synthesis of both the IBT6A Ibrutinib dimer and the IBT6A adduct ...
T70377 BAY 61-3606 HCl
BAY 61-3606 HCl is a cell-permeable, reversible inhibitor of spleen tyrosine kinase. BAY 61-3606 HCl can inhibit degranulation and block cytokine release from mast cells. Oral administration of BAY 61-3606 to rats was sh...
T62561 TRK-IN-17
TRK-IN-17 is a potent inhibitor of TRK. Among them is promyosin-related kinase (Trks), a member of the receptor tyrosine kinase family, which is activated by neurotrophic factors. Neurotrophic factors are a group of solu...
T63183 RET-IN-9
RET-IN-9 is a potent inhibitor of RET. RET kinase is a single-channel transmembrane receptor tyrosine kinase that plays an important role in the development of the kidney and enteric nervous system, as well as in the mai...
T63630 Gefitinib dihydrochloride
Gefitinib dihydrochloride is a potent, selective, orally active EGFR tyrosine kinase inhibitor (IC50: 33 nM). Gefitinib dihydrochloride selectively inhibits EGF-stimulated tumor cell growth with an IC50 value of 54 nM an...
T9814 JAK3/BTK-IN-1 JAK , BTK
JAK3/ BTk-in-1 is a dual JAK3/BTK inhibitor that specifically targets and inhibits Janus kinase 3 (JAK3) and Bruton's tyrosine kinase (BTK), two important targets in autoimmune diseases. JAK3/ BTk-in-1 simultaneously inh...
TMIH-0065 Acalabrutinib-d4
Acalabrutinib-d4 is a deuterated compound of Acalabrutinib. Acalabrutinib has a CAS number of 1420477-60-6. Acalabrutinib, also known as ACP-196, is an orally available inhibitor of Bruton’s tyrosine kinase (BTK) with po...
T36578 Boc-Lys(Ac)-AMC
Commendamide (N-acyl-3-hydroxypalmitoyl-glycine) is a newly discovered GPCR G2A/GPR132 agonist (EC50=11.8 μM) that isolated from Bacteroides vulgatus. [1] G2A/GPR132 belongs to the guanine nucleotide-binding protein (G p...
T36648 Tucatinib hemiethanolate
Tucatinib (Irbinitinib) hemiethanolate is a potent, orally active and selective HER2 inhibitor with an IC50 of 8 nM. Tucatinib hemiethanolate has nanomolar activity against purified HER2 enzyme and is approximately 500-f...

Compounds

TAK-659 hydrochloride
T4209
Synonym: TAK-659
Target: VEGFR, FLT, Tyrosine Kinases, JAK, Syk
AZ-Dyrk1B-33
T14364
Synonym: 3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine
Target: DYRK
Belizatinib
T4257
Synonym: TSR-011
Target: Trk receptor, ALK
Repotrectinib
T4071
Synonym: TPX-0005,TPX 0005,TPX0005
Target: Trk receptor, ROS, Src, ALK, ROS Kinase
GW 441756
T6052
Synonym:
Target: Apoptosis, Raf, Trk receptor, CDK
Entrectinib
T3678
Synonym: RXDX-101,NMS-E628
Target: Trk receptor, ROS, ALK, Autophagy, ROS Kinase
Altiratinib
T2054
Synonym: DCC-2701
Target: VEGFR, Tie-2, FLT, Trk receptor, c-Met/HGFR
Sitravatinib
T4349
Synonym: MG516,MGCD516
Target: Discoidin Domain Receptor (DDR), VEGFR, FLT, Trk receptor, TAM Receptor, c-Kit, Ephrin Receptor
Tyrphostin AG 879
T6712
Synonym: AG 879
Target: Apoptosis, EGFR, Trk receptor, HER, PDGFR
BMX-IN-1
T14692
Synonym: BMX kinase inhibitor
Target: BTK
Gilteritinib
T4409
Synonym: ASP2215
Target: FLT, TAM Receptor, c-Kit
AG-13958
T7493
Synonym: AG-013958
Target: VEGFR
SKLB 610
T1895
Synonym:
Target: VEGFR, FGFR, PDGFR
TIE-2/VEGFR-2 kinase-IN-5
T79860
Synonym:
Target: VEGFR, Tie-2
4SC-203
T9473
Synonym:
Target: FLT
LM22A-4
T7568
Synonym:
Target: Trk receptor
Falnidamol
TQ0271
Synonym: BIBX 1382
Target: EGFR
Syk Inhibitor II dihydrochloride
T4391
Synonym: Syk Inhibitor II (hydrochloride)
Target: Others, Tyrosine Kinases, Syk, PKC, BTK
CP-547632
T10870L
Synonym:
Target: VEGFR, FGFR, PDGFR, BTK
Acalabrutinib
T3626
Synonym: ACP-196
Target: BTK
Linifanib
T2514
Synonym: ABT-869,RG3635,AL-39324
Target: Apoptosis, c-Fms, VEGFR, FLT, CSF-1R, PDGFR, c-Kit, Autophagy
AD57 (hydrochloride)
T22552
Synonym:
Target: Others
Paltimatrectinib
T62447
Synonym: PBI-200,PPI-5278
Target: Trk receptor, Tyrosine Kinases
Quizartinib HCl
T71400
Synonym:
Target:
VEGFR2 Kinase Inhibitor II
T37079
Synonym:
Target:
Nedometinib
T78209
Synonym:
Target: MEK
CH7233163
T35334
Synonym:
Target: EGFR
(Rac)-IBT6A hydrochloride
T73942
Synonym:
Target:
BAY 61-3606 HCl
T70377
Synonym:
Target:
TRK-IN-17
T62561
Synonym:
Target:
RET-IN-9
T63183
Synonym:
Target:
Gefitinib dihydrochloride
T63630
Synonym:
Target:
JAK3/BTK-IN-1
T9814
Synonym:
Target: JAK, BTK
Acalabrutinib-d4
TMIH-0065
Synonym:
Target:
Boc-Lys(Ac)-AMC
T36578
Synonym:
Target:
Tucatinib hemiethanolate
T36648
Synonym:
Target:

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-06873 FLT3 Ligand Protein, Human, Recombinant Human E. coli
FLT3 Ligand Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.75 kDa and the accession number is P49771-1.
TMPY-03215 FLT3 Ligand Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
FLT3 Ligand Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 20.2 kDa and the accession number is P49771-1.
TMPY-03066 FLT3 Ligand Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
FLT3 Ligand Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.4 kDa and the accession number is P49772-1.
TMPY-00637 FLT1 Protein, Human, Recombinant (aa 1-328, His) Human HEK293 Cells
FLT1 Protein, Human, Recombinant (aa 1-328, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.6 kDa and the accession number is L7RSL3.
TMPY-01247 FLT3 Protein, Human, Recombinant (T227M, His) Human HEK293 Cells
FLT3 Protein, Human, Recombinant (T227M, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.7 kDa and the accession number is P36888-1.
TMPY-01936 VEGFR3/FLT4 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
VEGFR3/FLT4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86.4 kDa and the accession number is P35917-1.
TMPY-00949 VEGFR3/FLT4 Protein, Human, Recombinant (His) Human HEK293 Cells
VEGFR3/FLT4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86 kDa and the accession number is P35916-1.
TMPY-03299 FLT1 Protein, Rat, Recombinant (His) Rat HEK293 Cells
FLT1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 84 kDa and the accession number is P53767.
TMPY-05332 FLT3 Ligand Protein, Rat, Recombinant (His) Rat Baculovirus Insect Cells
FLT3 Ligand Protein, Rat, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 19.7 kDa and the accession number is NP_001292868.1.
TMPJ-00123 FLT3LG Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Fms-related tyrosine kinase 3 ligand(Flt3L) is a single-pass type I membrane protein and consists of 232 amino acids. Flt3L is a hematopoietic four helical bundle cytokine, structurally homologous to stem cell factor and...
TMPY-00119 FLT1 Protein, Human, Recombinant (hFc) Human HEK293 Cells
FLT1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.1 kDa and the accession number is P17948-4.
TMPY-02108 FLT1 Protein, Human, Recombinant (aa 1-756, His) Human HEK293 Cells
FLT1 Protein, Human, Recombinant (aa 1-756, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 83.7 kDa and the accession number is P17948-1.
TMPY-06780 FLT1 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
FLT1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 85.45 kDa and the accession number is P17948-1.
TMPY-06938 FLT3 Protein, Human, Recombinant (hFc & Avi), Biotinylated Human HEK293 Cells
FLT3 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 86.87 kDa and the accession number is NP_004110.2.
TMPY-05733 FLT1 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
FLT1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 84.2 kDa and the accession number is A0A0R4J0A4.
TMPY-05738 FLT3 Protein, Human, Recombinant (hFc) Human HEK293 Cells
FLT3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 85.06 kDa and the accession number is P36888-1.
TMPY-06665 FLT1 Protein, Mouse, Recombinant (His & Avi), Biotinylated Mouse HEK293 Cells
FLT1 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 88.34 kDa and the accession number is NP_034358.2.
TMPY-01937 VEGFR3/FLT4 Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
VEGFR3/FLT4 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 112 kDa and the accession number is P35917-1.
TMPJ-00403 EphB1 Protein, Human, Recombinant (hFc) Human HEK293 Cells
Ephrin Type-B Receptor 1 (EPHB1) is a single-pass type I membrane protein that belongs to the Ephrin-B family of receptor tyrosine kinases that is involved in embryonic nervous and vascular system development. EPHB1/EPHT...
TMPY-03704 FLT3 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
FLT3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 69.4 kDa and the accession number is EDL05832.1.
TMPJ-00088 EFNA1 Protein, Mouse, Recombinant (hFc & His) Mouse HEK293 Cells
Ephrin-A1 is a cell membrane protein and contains 1 ephrin RBD (ephrin receptor-binding) domain. EFNA1 belongs to the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor ...
TMPJ-00406 EphA8 Protein, Human, Recombinant (His) Human HEK293 Cells
EphA8, also known as Hek3 and Eek, is a 120 kDa glycosylated member of the Eph family of transmembrane receptor tyrosine kinases. The A and B classes of Eph proteins are distinguished by Ephrin ligand binding preference ...
TMPJ-00085 EFNA4 Protein, Human, Recombinant (hFc & His) Human HEK293 Cells
Ephrin-A4 is a member of the ephrin ligand family which binds members of the Eph receptor family. All ligands share a conserved extracellular sequence, which most likely corresponds to the receptor binding domain. Ephrin...
TMPJ-00224 EFNB2 Protein, Mouse, Recombinant (hFc & His) Mouse HEK293 Cells
Ephrin-B2 is a single-pass type I membrane protein and it contains 1 ephrin RBD (ephrin receptor-binding) domain. Ephrin-B2 belongs to the ephrin (EPH) family and it is cell surface transmembrane ligand for Eph receptors...
TMPY-01069 VEGFR3/FLT4 Protein, Human, Recombinant (hFc) Human HEK293 Cells
VEGFR3/FLT4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 111.3 kDa and the accession number is P35916-1.
TMPY-06620 VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 87.80 kDa and the accession number is NP_002011.2.
TMPJ-00114 EFNA3 Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
Ephrins-A3 belongs the Ephrins ligand family which involved in a variety of biological processes, especially in the nervous system and in erythropoiesis. It is shown that Ephrin-A3 is expressed in brain, skeletal muscle,...
TMPJ-00230 EFNB1 Protein, Mouse, Recombinant (hFc & His) Mouse HEK293 Cells
Mouse Ephrin-B1 is a single-pass type I membrane protein which belongs to the ephrin family. It contains an ephrin RBD (ephrin receptor-binding) domain, and expressed in heart, placenta, lung, liver, skeletal muscle, kid...
TMPJ-00791 HER2/ERBB2 Protein, Rat, Recombinant (E. coli, His) Rat E. coli
ERBB2 belongs to the protein kinase superfamily, Tyr protein kinase family and EGF receptor subfamily. It contains a protein kinase domain. ERBB2 is widely expressed in epithelial cells, and amplification and/or overexpr...
TMPJ-00546 EFNA1 Protein, Human, Recombinant (hFc) Human HEK293 Cells
Ephrin-A1 is a member of the A-type ephrin family of cell surface proteins that function as ligands for the A-type Eph receptor tyrosine kinase family. Ephrin-A1 can be induced by TNF and IL1B. Its expression levels can ...
TMPY-02028 RON/CD136 Protein, Human, Recombinant (His) Human HEK293 Cells
The tyrosine kinase receptor, macrophage-stimulating 1 receptor (MST1R), a c-met-related tyrosine kinase, also known as the Ron receptor or CD136, controls cell survival and motility programs related to invasive growth. ...
TMPY-04396 C-ABL/ABL1 Protein, Human, Recombinant (GST) Human Baculovirus Insect Cells
c-Abl belongs to the class of tyrosine kinases and is the prototype of a subfamily which includes two members, c-Abl and Arg (Abl-related gene). Both proteins are localized at the cell membrane, actin cytoskeleton and cy...
TMPY-04411 YES1 Protein, Human, Recombinant (His & GST) Human Baculovirus Insect Cells
Proto-oncogene tyrosine-protein kinase Yes, also known as Proto-oncogene c-Yes, p61-Yes and YES1, is a cytoplasm protein that belongs to the protein kinase superfamily, Tyr protein kinase family and SRC subfamily. YES1 /...
TMPK-00391 FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid‑box region con...
TMPK-00387 FGFR3 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid‑box region con...
TMPK-00634 MSPR/Ron Protein, Human, Recombinant (His) Human HEK293 Cells
Macrophage-stimulating protein (MSP) is a serum protein belonging to the plasminogen-related growth factor family. The specific receptor for MSP is the RON (recepteur d'origine nantais) receptor tyrosine kinase - a membe...
TMPK-00979 EPhA2 Protein, Cynomolgus, Recombinant (His & Avi) Cynomolgus HEK293 Cells
Ephrin type-A receptor 2 (EPHA2) is a receptor tyrosine kinase (RTK), whose over-expression has been observed in a variety of cancers, including breast cancer. EPHA2 expression may be causally related to tumorigenesis; t...
TMPK-00401 FGFR2 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region c...
TMPK-00980 EPhA2 Protein, Cynomolgus, Recombinant (hFc) Cynomolgus HEK293 Cells
Ephrin type-A receptor 2 (EPHA2) is a receptor tyrosine kinase (RTK), whose over-expression has been observed in a variety of cancers, including breast cancer. EPHA2 expression may be causally related to tumorigenesis; t...
TMPJ-01081 Dtk Protein, Human, Recombinant (His) Human HEK293 Cells
Axl (Ufo, Ark), Dtk (Sky, Tyro3, Rse, Brt) and Mer (human and mouse homologues of chicken cEyk)constitute a new receptor tyrosine kinase subfamily. The extracellular domain of these proteins contain two Ig-like motifs an...
TMPY-02708 NRG4 Protein, Human, Recombinant Human E. coli
NRG4 (neuregulin 4) is a member of the neuregulin protein family. The neuregulins consist of four structurally-related proteins that are part of the EGF family of proteins. It has been shown that these proteins have dive...
TMPJ-00290 GFR Alpha-2/GFRA2 Protein, Human, Recombinant (hFc & His) Human HEK293 Cells
GDNF family receptor alpha-2 is a glycosylphosphatidylinosito l (GPI)-linked cell surface receptor. It is part of the GDNF receptor family. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two s...
TMPJ-00194 IL-20RB Protein, Human, Recombinant (hFc) Human HEK293 Cells
Interleukin-20 receptor subunit beta(IL20RB) is a single-pass type I membrane protein and belongs to the type II cytokine receptor family. It contains 2 fibronectin type-III domains. There are two kinds of type II cytoki...
FLT3 Ligand Protein, Human, Recombinant
TMPY-06873
Species: Human
Expression System: E. coli
FLT3 Ligand Protein, Human, Recombinant (His)
TMPY-03215
Species: Human
Expression System: Baculovirus Insect Cells
FLT3 Ligand Protein, Mouse, Recombinant (hFc)
TMPY-03066
Species: Mouse
Expression System: HEK293 Cells
FLT1 Protein, Human, Recombinant (aa 1-328, His)
TMPY-00637
Species: Human
Expression System: HEK293 Cells
FLT3 Protein, Human, Recombinant (T227M, His)
TMPY-01247
Species: Human
Expression System: HEK293 Cells
VEGFR3/FLT4 Protein, Mouse, Recombinant (His)
TMPY-01936
Species: Mouse
Expression System: HEK293 Cells
VEGFR3/FLT4 Protein, Human, Recombinant (His)
TMPY-00949
Species: Human
Expression System: HEK293 Cells
FLT1 Protein, Rat, Recombinant (His)
TMPY-03299
Species: Rat
Expression System: HEK293 Cells
FLT3 Ligand Protein, Rat, Recombinant (His)
TMPY-05332
Species: Rat
Expression System: Baculovirus Insect Cells
FLT3LG Protein, Mouse, Recombinant (His)
TMPJ-00123
Species: Mouse
Expression System: HEK293 Cells
FLT1 Protein, Human, Recombinant (hFc)
TMPY-00119
Species: Human
Expression System: HEK293 Cells
FLT1 Protein, Human, Recombinant (aa 1-756, His)
TMPY-02108
Species: Human
Expression System: HEK293 Cells
FLT1 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-06780
Species: Human
Expression System: HEK293 Cells
FLT3 Protein, Human, Recombinant (hFc & Avi), Biotinylated
TMPY-06938
Species: Human
Expression System: HEK293 Cells
FLT1 Protein, Mouse, Recombinant (His)
TMPY-05733
Species: Mouse
Expression System: HEK293 Cells
FLT3 Protein, Human, Recombinant (hFc)
TMPY-05738
Species: Human
Expression System: HEK293 Cells
FLT1 Protein, Mouse, Recombinant (His & Avi), Biotinylated
TMPY-06665
Species: Mouse
Expression System: HEK293 Cells
VEGFR3/FLT4 Protein, Mouse, Recombinant (hFc)
TMPY-01937
Species: Mouse
Expression System: HEK293 Cells
EphB1 Protein, Human, Recombinant (hFc)
TMPJ-00403
Species: Human
Expression System: HEK293 Cells
FLT3 Protein, Mouse, Recombinant (His)
TMPY-03704
Species: Mouse
Expression System: HEK293 Cells
EFNA1 Protein, Mouse, Recombinant (hFc & His)
TMPJ-00088
Species: Mouse
Expression System: HEK293 Cells
EphA8 Protein, Human, Recombinant (His)
TMPJ-00406
Species: Human
Expression System: HEK293 Cells
EFNA4 Protein, Human, Recombinant (hFc & His)
TMPJ-00085
Species: Human
Expression System: HEK293 Cells
EFNB2 Protein, Mouse, Recombinant (hFc & His)
TMPJ-00224
Species: Mouse
Expression System: HEK293 Cells
VEGFR3/FLT4 Protein, Human, Recombinant (hFc)
TMPY-01069
Species: Human
Expression System: HEK293 Cells
VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-06620
Species: Human
Expression System: HEK293 Cells
EFNA3 Protein, Mouse, Recombinant (hFc)
TMPJ-00114
Species: Mouse
Expression System: HEK293 Cells
EFNB1 Protein, Mouse, Recombinant (hFc & His)
TMPJ-00230
Species: Mouse
Expression System: HEK293 Cells
HER2/ERBB2 Protein, Rat, Recombinant (E. coli, His)
TMPJ-00791
Species: Rat
Expression System: E. coli
EFNA1 Protein, Human, Recombinant (hFc)
TMPJ-00546
Species: Human
Expression System: HEK293 Cells
RON/CD136 Protein, Human, Recombinant (His)
TMPY-02028
Species: Human
Expression System: HEK293 Cells
C-ABL/ABL1 Protein, Human, Recombinant (GST)
TMPY-04396
Species: Human
Expression System: Baculovirus Insect Cells
YES1 Protein, Human, Recombinant (His & GST)
TMPY-04411
Species: Human
Expression System: Baculovirus Insect Cells
FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00391
Species: Human
Expression System: HEK293 Cells
FGFR3 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00387
Species: Human
Expression System: HEK293 Cells
MSPR/Ron Protein, Human, Recombinant (His)
TMPK-00634
Species: Human
Expression System: HEK293 Cells
EPhA2 Protein, Cynomolgus, Recombinant (His & Avi)
TMPK-00979
Species: Cynomolgus
Expression System: HEK293 Cells
FGFR2 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00401
Species: Human
Expression System: HEK293 Cells
EPhA2 Protein, Cynomolgus, Recombinant (hFc)
TMPK-00980
Species: Cynomolgus
Expression System: HEK293 Cells
Dtk Protein, Human, Recombinant (His)
TMPJ-01081
Species: Human
Expression System: HEK293 Cells
NRG4 Protein, Human, Recombinant
TMPY-02708
Species: Human
Expression System: E. coli
GFR Alpha-2/GFRA2 Protein, Human, Recombinant (hFc & His)
TMPJ-00290
Species: Human
Expression System: HEK293 Cells
IL-20RB Protein, Human, Recombinant (hFc)
TMPJ-00194
Species: Human
Expression System: HEK293 Cells
Cat No. Product Name
L2200 Tyrosine Kinase Inhibitor Library

1016 compounds
A unique collection of 1016 tyrosine kinase inhibitors for high throughput screening and high content screening for drug discovery in tyrosine kinase related diseases;
L9410 Covalent Inhibitor Library

1920 compounds
A unique collection of 1920 covalent Inhibitors and other molecules with common warheads like chloroacetyl,2-Chloropropionyl,Acryloyl,sulfonyl fluoride, alkyne,acrylamide, ketocarbonyl,disulfide bond, etc.
TargetMol